Obesity and stress can increase the risk of one of the most aggressive types of cancer, suggests a new study.
Researchers from the University of California Los Angeles (UCLA) discovered that stress-related neurotransmitters and obesity-related hormones activated CREB (cyclical AMP response-binding protein), of which was shown Cancer cells in the pancreas.
In the study, mice that ate a high -fat diet had a better chance of developing precancere lesions. When stress levels were also increased by social isolation, the lesions grew even more.
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The stress -related cancer risk was more pronounced in female mice.
Based on these findings, the researchers proposed to investigate the use of Existing medicines To reduce the risk of obesity and stress-related cancers.
Obesity and stress can increase the risk of one of the most aggressive types of cancer, suggests a new study. (Istock)
“Because β-adrenergic receptors play a crucial role in stress-related Cancer growthCommonly used beta -blockers, who are prescribed drugs for high blood pressure, can be reused to help reduce these effects, “a press release mentioned.
Pancreatic cancer is one of the deadliest types in the US, with a five -year survival percentage of only 13%.
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One of the biggest challenges with the disease is that it is often detected at a late stage in which the disease has already been advanced, according to Dr. Robert den, a radiation oncologist, professor of radiation oncology and Chief Medical Officer at Alpha Tau Medical in Israel.
“In contrast to some other cancers, there are no effective early screening tools, so by the time a patient is diagnosed, treatment options often limited his treatment options,” said Den, who was not involved in the study, to Fox News Digital.
“Unlike some other cancers, there are no effective early screening tools, so by the time a patient is diagnosed, treatment options are often limited.” (Istock)
The study strengthens the strong connection between the mind and body Because it related to the development of cancer, Den said.
“Stress and the corresponding routes can aggravate the progression of the disease, and we know that obesity feeds certain cancers, who may influence a patient’s response to the treatment,” he said.
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“In this case we see proof that stress and obesity Can contribute to the deterioration of pancreatic cancer, which has large implications for both prevention and treatment strategies. “
Maintaining a Heart-Healthy Diet And the food in moderation is essential, not only not only for cancer prevention, but also for overall health.
Pancreatic cancer is one of the deadliest types in the US, with a five -year survival percentage of only 13%. (Istock)
“Exercise is particularly crucial when tackling both obesity and stress,” he said. “Staying active is not only beneficial for physical health, but also an excellent way Reduce stress. “
Mindfulness can also play a key role in reducing the risk of cancer, the doctor advised.
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“Spending time outdoors can also improve both mentally and physical well -being, so I always encourage patients to find ways to be active, make contact with nature and to prioritize them General well -being“He said.
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Regarding pancreatic cancer Treatment, den, noted that there has been some progress in chemotherapy and surgical techniques, but “there has been no breakthrough yet.”
“Most immunotherapies, which have been revolutionary with other cancers, have not demonstrated the same promise in pancreatic cancer,” he said.
“Spending time outside can also improve both mentally and physical well -being, so I always encourage patients to find ways to be active, make contact with nature and give priority to their overall well -being,” said an oncologist. (Istock)
“The most important challenge is finding ways to help patients who are not candidates for surgery, because surgery remains the best line of defense.”
FOX News Digital reached the comments researchers.
